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Iron Accumulation in Deep Cortical Layers Accounts for MRI Signal Abnormalities in ALS: Correlating 7 Tesla MRI and Pathology

  • Justin Y. Kwan ,

    kwanjy@ninds.nih.gov

    Affiliation National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

  • Suh Young Jeong,

    Affiliation Molecular Medicine Program, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, United States of America

  • Peter Van Gelderen,

    Affiliation Advanced MRI Section, Laboratory of Functional and Molecular Imaging, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

  • Han-Xiang Deng,

    Affiliation Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America

  • Martha M. Quezado,

    Affiliation National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

  • Laura E. Danielian,

    Affiliation National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

  • John A. Butman,

    Affiliation Radiology and Imaging Sciences, Clinical Center, National Institutes of Health, Bethesda, Maryland, United States of America

  • Lingye Chen,

    Affiliation National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

  • Elham Bayat,

    Affiliation Department of Neurology, George Washington University, Washington, D. C., United States of America

  • James Russell,

    Affiliation Department of Neurology, University of Maryland, Baltimore, Maryland, United States of America

  • Teepu Siddique,

    Affiliation Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America

  • Jeff H. Duyn,

    Affiliation Advanced MRI Section, Laboratory of Functional and Molecular Imaging, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

  • Tracey A. Rouault,

    Affiliation Molecular Medicine Program, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, United States of America

  • Mary Kay Floeter

    Affiliation National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America

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