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Open Access

Peer-reviewed

Research Article

Alzheimer's Disease-Linked Mutations in Presenilin-1 Result in a Drastic Loss of Activity in Purified γ-Secretase Complexes

  • Matthias Cacquevel,
  • Lorène Aeschbach,
  • Jemila Houacine,
  • Patrick C. Fraering

    patrick.fraering@epfl.ch

    Affiliation École Polytechnique Fédérale de Lausanne, Brain Mind Institute, Laboratory of Molecular and Cellular Biology of Alzheimer's Disease, Lausanne, Switzerland

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