H₂O₂ Production Downstream of FLT3 Is Mediated by p22phox in the Endoplasmic Reticulum and Is Required for STAT5 Signalling

• John F. Woolley,

  Affiliation Tumour Biology Laboratory, Biochemistry Department, Bioscience Research Institute, University College, Cork, Ireland

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• Ruth Naughton,

  Affiliation Tumour Biology Laboratory, Biochemistry Department, Bioscience Research Institute, University College, Cork, Ireland

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• Joanna Stanicka,

  Affiliation Tumour Biology Laboratory, Biochemistry Department, Bioscience Research Institute, University College, Cork, Ireland

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• David R. Gough,

  Affiliation Tumour Biology Laboratory, Biochemistry Department, Bioscience Research Institute, University College, Cork, Ireland

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• Lavinia Bhatt,

  Affiliation Tumour Biology Laboratory, Biochemistry Department, Bioscience Research Institute, University College, Cork, Ireland

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• Bryan C. Dickinson,

  Affiliation Department of Chemistry, University of California, Berkeley, California, United States of America

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• Christopher J. Chang,

  Affiliation Howard Hughes Medical Institute, University of California, Berkeley, California, United States of America

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• Thomas G. Cotter

  * E-mail: t.cotter@ucc.ie

  Affiliation Tumour Biology Laboratory, Biochemistry Department, Bioscience Research Institute, University College, Cork, Ireland

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