A Model for How Signal Duration Can Determine Distinct Outcomes of Gene Transcription Programs

Open Access

Peer-reviewed

Research Article

Kevin D. Fowler,

Affiliation Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
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Vijay K. Kuchroo,

Affiliation Center for Neurologic Diseases, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts, United States of America
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Arup K. Chakraborty

* E-mail: arupc@mit.edu

Affiliations Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Ragon Institute of MGH, MIT, and Harvard, Boston, Massachusetts, United States of America
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Inflammation
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STAT signaling
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Signaling networks
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DNA transcription
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Transcription factors
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Genetic networks
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Macrophages
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Cytokines
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