Lung Adenocarcinoma of Never Smokers and Smokers Harbor Differential Regions of Genetic Alteration and Exhibit Different Levels of Genomic Instability

• Kelsie L. Thu ,

  * E-mail: kthu@bccrc.ca

  Affiliation Department of Integrative Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada

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• Emily A. Vucic,

  Affiliation Department of Integrative Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada

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• Raj Chari,

  Affiliations Department of Integrative Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

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• Wei Zhang,

  Affiliation Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

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• William W. Lockwood,

  Affiliations Department of Integrative Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada, Cancer Genetics Branch National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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• John C. English,

  Affiliation Department of Pathology, Vancouver General Hospital, Vancouver, British Columbia, Canada

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• Rong Fu,

  Affiliation Division of Public Health Sciences, Fred Hutchinson Cancer Research Centre, Seattle, Washington, United States of America

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• Pei Wang,

  Affiliation Division of Public Health Sciences, Fred Hutchinson Cancer Research Centre, Seattle, Washington, United States of America

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• Ziding Feng,

  Affiliation Division of Public Health Sciences, Fred Hutchinson Cancer Research Centre, Seattle, Washington, United States of America

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• Calum E. MacAulay,

  Affiliation Department of Integrative Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada

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• Adi F. Gazdar,

  Affiliation Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

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• Stephen Lam,

  Affiliation Department of Integrative Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada

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• Wan L. Lam

  Affiliation Department of Integrative Oncology, British Columbia Cancer Research Centre, Vancouver, British Columbia, Canada

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