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Research Article

Defects in Mitochondrial Dynamics and Metabolomic Signatures of Evolving Energetic Stress in Mouse Models of Familial Alzheimer's Disease

  • Eugenia Trushina mail,

    Trushina.eugenia@mayo.edu

    Affiliation: Department of Molecular Pharmacology and Experimental Therapeutics and Neurology, Mayo Clinic, Rochester, Minnesota, United States of America

    X
  • Emirhan Nemutlu,

    Affiliation: Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, United States of America

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  • Song Zhang,

    Affiliation: Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, United States of America

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  • Trace Christensen,

    Affiliation: Electron Microscopy Core Facility, Mayo Clinic, Rochester, Minnesota, United States of America

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  • Jon Camp,

    Affiliation: Biomedical Imaging Resource, Mayo Clinic, Rochester, Minnesota, United States of America

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  • Janny Mesa,

    Affiliation: Department of Molecular Pharmacology and Experimental Therapeutics and Neurology, Mayo Clinic, Rochester, Minnesota, United States of America

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  • Ammar Siddiqui,

    Affiliation: Department of Molecular Pharmacology and Experimental Therapeutics and Neurology, Mayo Clinic, Rochester, Minnesota, United States of America

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  • Yasushi Tamura,

    Affiliation: Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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  • Hiromi Sesaki,

    Affiliation: Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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  • Thomas M. Wengenack,

    Affiliation: Departments of Neurology and Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, United States of America

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  • Petras P. Dzeja,

    Affiliation: Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, United States of America

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  • Joseph F. Poduslo

    Affiliation: Departments of Neurology and Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, United States of America

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  • Published: February 29, 2012
  • DOI: 10.1371/journal.pone.0032737

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