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Cytotoxicity of CD56bright NK Cells towards Autologous Activated CD4+ T Cells Is Mediated through NKG2D, LFA-1 and TRAIL and Dampened via CD94/NKG2A

  • Natasja Nielsen,

    Affiliations Translational Immunology, Novo Nordisk A/S, Måløv, Denmark, Department of Microbiology and Immunology and the Cancer Research Institute, University of California San Francisco, San Francisco, California, United States of America

  • Niels Ødum,

    Affiliation Department of Biology, Faculty of Science, University of Copenhagen, Copenhagen, Denmark

  • Birgitte Ursø,

    Affiliation Monocyte Biology, Inflammation Biology, Novo Nordisk A/S, Måløv, Denmark

  • Lewis L. Lanier,

    Affiliation Department of Microbiology and Immunology and the Cancer Research Institute, University of California San Francisco, San Francisco, California, United States of America

  • Pieter Spee

    spee@novonordisk.com

    Affiliation Translational Immunology, Novo Nordisk A/S, Måløv, Denmark

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