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Research Article

Cholesteryl Ester Transfer Protein (CETP) Polymorphisms Affect mRNA Splicing, HDL Levels, and Sex-Dependent Cardiovascular Risk

  • Audrey C. Papp mail,

    papp.2@osu.edu

    Affiliation: Program in Pharmacogenomics, Department of Pharmacology, College of Medicine, The Ohio State University, Columbus, Ohio, United States of America

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  • Julia K. Pinsonneault,

    Affiliation: Program in Pharmacogenomics, Department of Pharmacology, College of Medicine, The Ohio State University, Columbus, Ohio, United States of America

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  • Danxin Wang,

    Affiliation: Program in Pharmacogenomics, Department of Pharmacology, College of Medicine, The Ohio State University, Columbus, Ohio, United States of America

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  • Leslie C. Newman,

    Affiliation: Program in Pharmacogenomics, Department of Pharmacology, College of Medicine, The Ohio State University, Columbus, Ohio, United States of America

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  • Yan Gong,

    Affiliation: Department of Pharmacy Practice, College of Pharmacy, University of Florida, Gainesville, Florida, United States of America

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  • Julie A. Johnson,

    Affiliation: Department of Pharmacy Practice, College of Pharmacy, University of Florida, Gainesville, Florida, United States of America

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  • Carl J. Pepine,

    Affiliation: College of Medicine, Division of Cardiovascular Medicine, University of Florida, Gainesville Florida, United States of America

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  • Meena Kumari,

    Affiliation: Genetic Epidemiology Group, Department of Epidemiology and Public Health, University College London, London, United Kingdom

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  • Aroon D. Hingorani,

    Affiliation: Genetic Epidemiology Group, Department of Epidemiology and Public Health, University College London, London, United Kingdom

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  • Philippa J. Talmud,

    Affiliation: Centre for Cardiovascular Genetics, BHF Laboratories, Institute Cardiovascular Science, University College London, London, United Kingdom

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  • Sonia Shah,

    Affiliation: Genetic Epidemiology Group, Department of Epidemiology and Public Health, University College London, London, United Kingdom

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  • Steve E. Humphries,

    Affiliations: Centre for Cardiovascular Genetics, BHF Laboratories, Institute Cardiovascular Science, University College London, London, United Kingdom, UCL Genetics Institute, University College London, London, United Kingdom

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  • Wolfgang Sadee

    Affiliation: Program in Pharmacogenomics, Department of Pharmacology, College of Medicine, The Ohio State University, Columbus, Ohio, United States of America

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  • Published: March 05, 2012
  • DOI: 10.1371/journal.pone.0031930

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