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Open Access

Peer-reviewed

Research Article

Losartan Slows Pancreatic Tumor Progression and Extends Survival of SPARC-Null Mice by Abrogating Aberrant TGFβ Activation

  • Shanna A. Arnold,

    Current address: Departments of Pathology and Cancer Biology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

    Affiliation Division of Surgical Oncology, Departments of Surgery and Pharmacology, Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

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  • Lee B. Rivera,

    Current address: Department of Neurological Surgery, University of California San Francisco School of Medicine, San Francisco, California, United States of America

    Affiliation Division of Surgical Oncology, Departments of Surgery and Pharmacology, Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

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  • Juliet G. Carbon,

    Affiliation Division of Surgical Oncology, Departments of Surgery and Pharmacology, Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

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  • Jason E. Toombs,

    Affiliation Division of Surgical Oncology, Departments of Surgery and Pharmacology, Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

    ⨯
  • Chi-Lun Chang,

    Affiliation Division of Surgical Oncology, Departments of Surgery and Pharmacology, Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

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  • Amy D. Bradshaw,

    Affiliation Department of Medicine, Medical University of South Carolina, Charleston, South Carolina, United States of America

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  • Rolf A. Brekken

    rolf.brekken@utsouthwestern.edu

    Affiliation Division of Surgical Oncology, Departments of Surgery and Pharmacology, Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

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