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Charged and Hydrophobic Surfaces on the A Chain of Shiga-Like Toxin 1 Recognize the C-Terminal Domain of Ribosomal Stalk Proteins

  • Andrew J. McCluskey,

    Affiliation Department of Pharmaceutical Sciences, University of Toronto, Toronto, Ontario, Canada

  • Eleonora Bolewska-Pedyczak,

    Affiliation Sunnybrook Research Institute, Toronto, Ontario, Canada

  • Nick Jarvik,

    Affiliation Banting and Best Department of Medical Research, Terrence Donnelly Center for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada

  • Gang Chen,

    Affiliation Banting and Best Department of Medical Research, Terrence Donnelly Center for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada

  • Sachdev S. Sidhu,

    Affiliation Banting and Best Department of Medical Research, Terrence Donnelly Center for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario, Canada

  • Jean Gariépy

    gariepy@sri.utoronto.ca

    Affiliations Department of Pharmaceutical Sciences, University of Toronto, Toronto, Ontario, Canada, Sunnybrook Research Institute, Toronto, Ontario, Canada, Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada

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