Transcriptional Silencing of the Wnt-Antagonist DKK1 by Promoter Methylation Is Associated with Enhanced Wnt Signaling in Advanced Multiple Myeloma

• Kinga A. Kocemba ,

  Contributed equally to this work with: Kinga A. Kocemba, Richard W. J. Groen

  Affiliation Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

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• Richard W. J. Groen ,

  Contributed equally to this work with: Kinga A. Kocemba, Richard W. J. Groen

  Affiliation Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

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• Harmen van Andel,

  Affiliation Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

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• Marie José Kersten,

  Affiliation Department of Hematology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

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• Karène Mahtouk,

  Affiliation Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

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• Marcel Spaargaren ,

  ¶These authors also contributed equally to this work.

  Affiliation Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

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• Steven T. Pals

  * E-mail: s.t.pals@amc.uva.nl

  Affiliation Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

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