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Research Article

Sca-1+ Cardiosphere-Derived Cells Are Enriched for Isl1-Expressing Cardiac Precursors and Improve Cardiac Function after Myocardial Injury

  • Jianqin Ye,

    Affiliation: Division of Cardiology, Department of Medicine, University of California San Francisco, San Francisco, California, United States of America

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  • Andrew Boyle,

    Affiliations: Division of Cardiology, Department of Medicine, University of California San Francisco, San Francisco, California, United States of America, Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, California, United States of America

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  • Henry Shih,

    Affiliation: Division of Cardiology, Department of Medicine, University of California San Francisco, San Francisco, California, United States of America

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  • Richard E. Sievers,

    Affiliation: Division of Cardiology, Department of Medicine, University of California San Francisco, San Francisco, California, United States of America

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  • Yan Zhang,

    Affiliation: Division of Cardiology, Department of Medicine, University of California San Francisco, San Francisco, California, United States of America

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  • Megha Prasad,

    Affiliation: Division of Cardiology, Department of Medicine, University of California San Francisco, San Francisco, California, United States of America

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  • Hua Su,

    Affiliation: Department of Anesthesia and Perioperative Care, University of California San Francisco, San Francisco, California, United States of America

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  • Yan Zhou,

    Affiliation: Department of Cell and Tissue Biology, University of California San Francisco, San Francisco, California, United States of America

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  • William Grossman,

    Affiliations: Division of Cardiology, Department of Medicine, University of California San Francisco, San Francisco, California, United States of America, Cardiovascular Research Institute, University of California San Francisco, San Francisco, California, United States of America

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  • Harold S. Bernstein,

    Affiliations: Cardiovascular Research Institute, University of California San Francisco, San Francisco, California, United States of America, Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, California, United States of America, Department of Pediatrics, University of California San Francisco, San Francisco, California, United States of America

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  • Yerem Yeghiazarians mail

    yeghiaza@medicine.ucsf.edu

    Affiliations: Division of Cardiology, Department of Medicine, University of California San Francisco, San Francisco, California, United States of America, Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, California, United States of America

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  • Published: January 17, 2012
  • DOI: 10.1371/journal.pone.0030329

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