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Open Access

Peer-reviewed

Research Article

Ex Vivo Expansion of Human CD8+ T Cells Using Autologous CD4+ T Cell Help

  • Marcus O. Butler,

    Affiliations Department of Medical Oncology, Dana-Farber Cancer Institute, Massachusetts, United States of America, Department of Medicine, Brigham and Women's Hospital, Massachusetts, United States of America, Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Osamu Imataki,

    Affiliations Department of Medical Oncology, Dana-Farber Cancer Institute, Massachusetts, United States of America, Department of Medicine, Brigham and Women's Hospital, Massachusetts, United States of America, Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Yoshihiro Yamashita,

    Affiliation Division of Functional Genomics, Jichi Medical University, Tochigi, Japan

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  • Makito Tanaka,

    Affiliations Department of Medical Oncology, Dana-Farber Cancer Institute, Massachusetts, United States of America, Department of Medicine, Brigham and Women's Hospital, Massachusetts, United States of America, Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Sascha Ansén,

    Affiliations Department of Medical Oncology, Dana-Farber Cancer Institute, Massachusetts, United States of America, Department of Medicine, Brigham and Women's Hospital, Massachusetts, United States of America, Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Alla Berezovskaya,

    Affiliation Department of Medical Oncology, Dana-Farber Cancer Institute, Massachusetts, United States of America

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  • Genita Metzler,

    Affiliation Department of Medical Oncology, Dana-Farber Cancer Institute, Massachusetts, United States of America

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  • Matthew I. Milstein,

    Affiliation Department of Medical Oncology, Dana-Farber Cancer Institute, Massachusetts, United States of America

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  • Mary M. Mooney,

    Affiliation Department of Medical Oncology, Dana-Farber Cancer Institute, Massachusetts, United States of America

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  • Andrew P. Murray,

    Affiliation Department of Medical Oncology, Dana-Farber Cancer Institute, Massachusetts, United States of America

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  • Hiroyuki Mano,

    Affiliations Division of Functional Genomics, Jichi Medical University, Tochigi, Japan, Department of Medical Genomics, University of Tokyo, Tokyo, Japan

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  • Lee M. Nadler,

    Affiliations Department of Medical Oncology, Dana-Farber Cancer Institute, Massachusetts, United States of America, Department of Medicine, Brigham and Women's Hospital, Massachusetts, United States of America, Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Naoto Hirano

    nhirano@uhnres.utoronto.ca

    Affiliations Department of Medical Oncology, Dana-Farber Cancer Institute, Massachusetts, United States of America, Department of Medicine, Brigham and Women's Hospital, Massachusetts, United States of America, Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America, Immune Therapy Program, Campbell Family Institute for Breast Cancer Research, Campbell Family Cancer Research, Ontario Cancer Institute, Toronto, Ontario, Canada, Department of Immunology, University of Toronto, Toronto, Ontario, Canada

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