The Ubiquitin Peptidase UCHL1 Induces G0/G1 Cell Cycle Arrest and Apoptosis Through Stabilizing p53 and Is Frequently Silenced in Breast Cancer

• Tingxiu Xiang,

  Affiliation Molecular Oncology and Epigenetics Laboratory, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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• Lili Li,

  Affiliation Cancer Epigenetics Laboratory, Department of Clinical Oncology, Sir YK Pao Center for Cancer, Li Ka Shing Institute of Health Sciences, CUHK Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong, China

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• Xuedong Yin,

  Affiliation Molecular Oncology and Epigenetics Laboratory, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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• Chenfu Yuan,

  Affiliation Molecular Oncology and Epigenetics Laboratory, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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• Cui Tan,

  Affiliation Molecular Oncology and Epigenetics Laboratory, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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• Xianwei Su,

  Affiliation Cancer Epigenetics Laboratory, Department of Clinical Oncology, Sir YK Pao Center for Cancer, Li Ka Shing Institute of Health Sciences, CUHK Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong, China

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• Lei Xiong,

  Affiliation Cancer Epigenetics Laboratory, Department of Clinical Oncology, Sir YK Pao Center for Cancer, Li Ka Shing Institute of Health Sciences, CUHK Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong, China

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• Thomas C. Putti,

  Affiliation Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore

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• Michael Oberst,

  Affiliation Signal Transduction Section, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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• Kathleen Kelly,

  Affiliation Signal Transduction Section, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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• Guosheng Ren ,

  * E-mail: rgs726@163.com (GR); qtao@clo.cuhk.edu.hk (QT)

  Affiliation Molecular Oncology and Epigenetics Laboratory, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China

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• Qian Tao

  * E-mail: rgs726@163.com (GR); qtao@clo.cuhk.edu.hk (QT)

  Affiliations Molecular Oncology and Epigenetics Laboratory, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China, Cancer Epigenetics Laboratory, Department of Clinical Oncology, Sir YK Pao Center for Cancer, Li Ka Shing Institute of Health Sciences, CUHK Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong, China

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