STAT1 Hyperphosphorylation and Defective IL12R/IL23R Signaling Underlie Defective Immunity in Autosomal Dominant Chronic Mucocutaneous Candidiasis

• Sanne P. Smeekens ,

  Contributed equally to this work with: Sanne P. Smeekens, Theo S. Plantinga, Frank L. van de Veerdonk

  Affiliations Department of Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands, Nijmegen Institute for Infection, Inflammation, and Immunity (N4i), Nijmegen, The Netherlands

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• Theo S. Plantinga ,

  Contributed equally to this work with: Sanne P. Smeekens, Theo S. Plantinga, Frank L. van de Veerdonk

  Affiliations Department of Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands, Nijmegen Institute for Infection, Inflammation, and Immunity (N4i), Nijmegen, The Netherlands

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• Frank L. van de Veerdonk ,

  Contributed equally to this work with: Sanne P. Smeekens, Theo S. Plantinga, Frank L. van de Veerdonk

  Affiliations Department of Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands, Nijmegen Institute for Infection, Inflammation, and Immunity (N4i), Nijmegen, The Netherlands

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• Bas Heinhuis,

  Affiliation Department of Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands

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• Alexander Hoischen,

  Affiliation Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands

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• Leo A. B. Joosten,

  Affiliations Department of Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands, Nijmegen Institute for Infection, Inflammation, and Immunity (N4i), Nijmegen, The Netherlands

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• Peter D. Arkwright,

  Affiliation Royal Manchester Hospital, University of Manchester, Manchester, United Kingdom

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• Andrew Gennery,

  Affiliation Institute for Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom

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• Bart Jan Kullberg,

  Affiliations Department of Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands, Nijmegen Institute for Infection, Inflammation, and Immunity (N4i), Nijmegen, The Netherlands

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• Joris A. Veltman,

  Affiliation Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands

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• Desa Lilic,

  Affiliation Institute for Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom

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• Jos W. M. van der Meer ,

  ¶This author also contributed equally to this work.

  Affiliations Department of Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands, Nijmegen Institute for Infection, Inflammation, and Immunity (N4i), Nijmegen, The Netherlands

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• Mihai G. Netea

  * E-mail: m.netea@aig.umcn.nl

  Affiliations Department of Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands, Nijmegen Institute for Infection, Inflammation, and Immunity (N4i), Nijmegen, The Netherlands

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