Anti-Proteinase 3 Anti-Neutrophil Cytoplasm Autoantibodies Recapitulate Systemic Vasculitis in Mice with a Humanized Immune System

• Mark A. Little ,

  Contributed equally to this work with: Mark A. Little, Bahjat Al-Ani, Shuyu Ren

  * E-mail: jeremysd@u.washington.edu (JSD) ; mark.little@ucl.ac.uk (ML)

  Affiliation Centre for Nephrology, Royal Free Hospital, University College London, London, United Kingdom

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• Bahjat Al-Ani ,

  Contributed equally to this work with: Mark A. Little, Bahjat Al-Ani, Shuyu Ren

  Current address: Department of Physiology, College of Medicine, King Khalid University, Abha, Saudi Arabia

  Affiliation Renal Institute of Birmingham, School of Infection, Immunology and Inflammation, University of Birmingham, Birmingham, United Kingdom

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• Shuyu Ren ,

  Contributed equally to this work with: Mark A. Little, Bahjat Al-Ani, Shuyu Ren

  Affiliation Division of Nephrology, Department of Medicine, Center for Lung Biology and Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, Washington, United States of America

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• Hamad Al-Nuaimi,

  Affiliation Renal Institute of Birmingham, School of Infection, Immunology and Inflammation, University of Birmingham, Birmingham, United Kingdom

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• Maurilo Leite Jr,

  Affiliations Division of Nephrology, Department of Medicine, Center for Lung Biology and Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, Washington, United States of America, Division of Nephrology, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil

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• Charles E. Alpers,

  Affiliation Department of Pathology, University of Washington, Seattle, Washington, United States of America

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• Caroline O. Savage,

  Affiliations Renal Institute of Birmingham, School of Infection, Immunology and Inflammation, University of Birmingham, Birmingham, United Kingdom, GlaxoSmithKline UK Ltd, Uxbridge, United Kingdom

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• Jeremy S. Duffield

  * E-mail: jeremysd@u.washington.edu (JSD) ; mark.little@ucl.ac.uk (ML)

  Affiliation Division of Nephrology, Department of Medicine, Center for Lung Biology and Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, Washington, United States of America

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