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Research Article

Children Who Acquire HIV Infection Perinatally Are at Higher Risk of Early Death than Those Acquiring Infection through Breastmilk: A Meta-Analysis

  • Renaud Becquet mail,

    Renaud.Becquet@isped.u-bordeaux2.fr

    Affiliations: Institut National de la Santé et de la Recherche Médicale (INSERM), Unité 897, Centre de Recherche “Epidémiologie et Biostatistique”, Bordeaux, France, Institut de Santé Publique Epidémiologie Développement (ISPED), Université Victor Segalen Bordeaux 2, Bordeaux, France

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  • Milly Marston,

    Affiliation: London School of Hygiene and Tropical Medicine, London, United Kingdom

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  • François Dabis,

    Affiliations: Institut National de la Santé et de la Recherche Médicale (INSERM), Unité 897, Centre de Recherche “Epidémiologie et Biostatistique”, Bordeaux, France, Institut de Santé Publique Epidémiologie Développement (ISPED), Université Victor Segalen Bordeaux 2, Bordeaux, France

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  • Lawrence H. Moulton,

    Affiliation: Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America

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  • Glenda Gray,

    Affiliation: Perinatal HIV Research Unit (PHRU), University of the Witwatersrand, Soweto, South Africa

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  • Hoosen M. Coovadia,

    Affiliation: HIV Management, Maternal, Adolescent and Child Unit, University of the Witwatersrand, Soweto, South Africa

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  • Max Essex,

    Affiliation: Department of Immunology and Infectious Diseases, Harvard School of Public Health AIDS Initiative, Boston, Massachusetts, United States of America

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  • Didier K. Ekouevi,

    Affiliation: PAC-CI program, ANRS site in Côte d'Ivoire, Abidjan, Côte d'Ivoire

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  • Debra Jackson,

    Affiliation: School of Public Health, University of the Western Cape, Cape Town, South Africa

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  • Anna Coutsoudis,

    Affiliation: Department of Paediatrics and Child Health, University of KwaZulu-Natal, South Africa

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  • Charles Kilewo,

    Affiliation: Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania

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  • Valériane Leroy,

    Affiliations: Institut National de la Santé et de la Recherche Médicale (INSERM), Unité 897, Centre de Recherche “Epidémiologie et Biostatistique”, Bordeaux, France, Institut de Santé Publique Epidémiologie Développement (ISPED), Université Victor Segalen Bordeaux 2, Bordeaux, France

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  • Stefan Z. Wiktor,

    Affiliation: RETRO-CI project, Centers for Disease Control and Prevention, Global HIV/AIDS Program, Abidjan, Côte d'Ivoire

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  • Ruth Nduati,

    Affiliation: Department of Pediatrics, University of Nairobi, Nairobi, Kenya

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  • Philippe Msellati,

    Affiliation: Service de Pédiatrie, CHU Sourô Sanou, Bobo Dioulasso, Burkina Faso

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  • Basia Zaba,

    Affiliation: London School of Hygiene and Tropical Medicine, London, United Kingdom

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  • Peter D. Ghys,

    Affiliation: UNAIDS, Epidemiology and Analysis Division, Geneva, Switzerland

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  • Marie-Louise Newell,

    Affiliations: Africa Centre for Health and Population Studies, University of KwaZulu-Natal, Somkhele, South Africa, Centre for Paediatric Epidemiology and Biostatistics, University College London, Institute of Child Health, London, United Kingdom

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  • the UNAIDS Child survival group

    See the Acknowledgments section for the detailed constitution of the group.

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  • Published: February 23, 2012
  • DOI: 10.1371/journal.pone.0028510

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