Concanavalin A/IFN-Gamma Triggers Autophagy-Related Necrotic Hepatocyte Death through IRGM1-Mediated Lysosomal Membrane Disruption

Open Access

Peer-reviewed

Research Article

Chih-Peng Chang,

Affiliations Department of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan, Taiwan, Infectious Disease and Signaling Research Center, College of Medicine, National Cheng Kung University, Tainan, Taiwan
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Ming-Chen Yang,

Affiliation Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan
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Huan-Yao Lei

* E-mail: hylei@mail.ncku.edu.tw

Affiliations Department of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan, Taiwan, Institute of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan, Infectious Disease and Signaling Research Center, College of Medicine, National Cheng Kung University, Tainan, Taiwan
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Autophagic cell death
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Necrotic cell death
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Apoptosis
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Lysosomes
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Hepatoma cells
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Hepatocytes
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Necrosis
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Small interfering RNA
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