Inhibition of Hedgehog Signaling Antagonizes Serous Ovarian Cancer Growth in a Primary Xenograft Model

• Christopher K. McCann,

  Affiliations Department of Vincent Obstetrics and Gynecology, Vincent Center for Reproductive Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Division of Gynecologic Oncology, Department of Vincent Obstetrics and Gynecology, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

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• Whitfield B. Growdon,

  Affiliations Department of Vincent Obstetrics and Gynecology, Vincent Center for Reproductive Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Division of Gynecologic Oncology, Department of Vincent Obstetrics and Gynecology, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

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• Kashmira Kulkarni-Datar,

  Affiliations Department of Vincent Obstetrics and Gynecology, Vincent Center for Reproductive Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

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• Michael D. Curley,

  Affiliations Department of Vincent Obstetrics and Gynecology, Vincent Center for Reproductive Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

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• Anne M. Friel,

  Affiliations Department of Vincent Obstetrics and Gynecology, Vincent Center for Reproductive Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

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• Jennifer L. Proctor,

  Affiliation Infinity Pharmaceuticals, Cambridge, Massachusetts, United States of America

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• Hana Sheikh,

  Affiliation Infinity Pharmaceuticals, Cambridge, Massachusetts, United States of America

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• Igor Deyneko,

  Affiliation Infinity Pharmaceuticals, Cambridge, Massachusetts, United States of America

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• Jeanne A. Ferguson,

  Affiliation Infinity Pharmaceuticals, Cambridge, Massachusetts, United States of America

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• Vinod Vathipadiekal,

  Affiliations Harvard Medical School, Boston, Massachusetts, United States of America, Division of Hematology-Oncology, Massachusetts General Hospital Cancer Center, Boston, Massachusetts, United States of America

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• Michael J. Birrer,

  Affiliations Harvard Medical School, Boston, Massachusetts, United States of America, Division of Hematology-Oncology, Massachusetts General Hospital Cancer Center, Boston, Massachusetts, United States of America

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• Darrell R. Borger,

  Affiliations Harvard Medical School, Boston, Massachusetts, United States of America, Division of Hematology-Oncology, Massachusetts General Hospital Cancer Center, Boston, Massachusetts, United States of America

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• Gayatry Mohapatra,

  Affiliations Harvard Medical School, Boston, Massachusetts, United States of America, Division of Hematology-Oncology, Massachusetts General Hospital Cancer Center, Boston, Massachusetts, United States of America

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• Lawrence R. Zukerberg,

  Affiliations Harvard Medical School, Boston, Massachusetts, United States of America, Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts, United States of America

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• Rosemary Foster,

  Affiliations Department of Vincent Obstetrics and Gynecology, Vincent Center for Reproductive Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

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• John R. MacDougall,

  Affiliation Infinity Pharmaceuticals, Cambridge, Massachusetts, United States of America

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•  [ ... ],
• Bo R. Rueda

  * E-mail: brueda@partners.org

  Affiliations Department of Vincent Obstetrics and Gynecology, Vincent Center for Reproductive Biology, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Division of Gynecologic Oncology, Department of Vincent Obstetrics and Gynecology, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

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