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Research Article

Induction of Antibodies in Rhesus Macaques That Recognize a Fusion-Intermediate Conformation of HIV-1 gp41

  • S. Moses Dennison,

    Affiliation: Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, United States of America

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  • Laura L. Sutherland,

    Affiliation: Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, United States of America

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  • Frederick H. Jaeger,

    Affiliation: Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, United States of America

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  • Kara M. Anasti,

    Affiliation: Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, United States of America

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  • Robert Parks,

    Affiliation: Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, United States of America

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  • Shelley Stewart,

    Affiliation: Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, United States of America

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  • Cindy Bowman,

    Affiliation: Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, United States of America

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  • Shi-Mao Xia,

    Affiliation: Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, United States of America

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  • Ruijun Zhang,

    Affiliation: Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, United States of America

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  • Xiaoying Shen,

    Affiliation: Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, United States of America

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  • Richard M. Scearce,

    Affiliation: Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, United States of America

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  • Gilad Ofek,

    Affiliation: Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Yongping Yang,

    Affiliation: Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Peter D. Kwong,

    Affiliation: Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Sampa Santra,

    Affiliation: Department of Medicine, Beth Israel Deaconess Medical Center, Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Hua-Xin Liao,

    Affiliation: Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, United States of America

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  • Georgia Tomaras,

    Affiliation: Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, United States of America

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  • Norman L. Letvin,

    Affiliation: Department of Medicine, Beth Israel Deaconess Medical Center, Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Bing Chen,

    Affiliation: Division of Molecular Medicine, Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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  • S. Munir Alam mail,

    alam0004@mc.duke.edu (SMA); hayne002@mc.duke.edu (BFH)

    Affiliation: Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, United States of America

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  • Barton F. Haynes mail

    alam0004@mc.duke.edu (SMA); hayne002@mc.duke.edu (BFH)

    Affiliation: Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, United States of America

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  • Published: November 30, 2011
  • DOI: 10.1371/journal.pone.0027824

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