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Open Access

Peer-reviewed

Research Article

Human Engineered Heart Tissue as a Versatile Tool in Basic Research and Preclinical Toxicology

  • Sebastian Schaaf,

    Affiliation Department of Experimental Pharmacology and Toxicology, Cardiovascular Research Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

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  • Aya Shibamiya,

    Affiliation Department of Experimental Pharmacology and Toxicology, Cardiovascular Research Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

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  • Marco Mewe,

    Affiliation Department of Pharmacology for Pharmacists, Cardiovascular Research Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

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  • Alexandra Eder,

    Affiliation Department of Experimental Pharmacology and Toxicology, Cardiovascular Research Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

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  • Andrea Stöhr,

    Affiliation Department of Experimental Pharmacology and Toxicology, Cardiovascular Research Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

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  • Marc N. Hirt,

    Affiliation Department of Experimental Pharmacology and Toxicology, Cardiovascular Research Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

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  • Thomas Rau,

    Affiliation Department of Experimental Pharmacology and Toxicology, Cardiovascular Research Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

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  • Wolfram-Hubertus Zimmermann,

    Current address: Department of Pharmacology, Heart Research Center Göttingen, Georg-August-University Göttingen, Göttingen, Germany

    Affiliation Department of Experimental Pharmacology and Toxicology, Cardiovascular Research Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

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  • Lenard Conradi,

    Affiliation Department of Cardiovascular Surgery, Cardiovascular Research Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

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  • Thomas Eschenhagen ,

    Contributed equally to this work with: Thomas Eschenhagen, Arne Hansen

    Affiliation Department of Experimental Pharmacology and Toxicology, Cardiovascular Research Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

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  • Arne Hansen

    Contributed equally to this work with: Thomas Eschenhagen, Arne Hansen

    ar.hansen@uke.de

    Affiliation Department of Experimental Pharmacology and Toxicology, Cardiovascular Research Center, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

    ⨯

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