Can Linear Regression Modeling Help Clinicians in the Interpretation of Genotypic Resistance Data? An Application to Derive a Lopinavir-Score

• Alessandro Cozzi-Lepri ,

  * E-mail: aclepri@ccbr.umn.edu

  Affiliations Department of Infection and Population Health, Division of Population Health, UCL Medical School, Royal Free Campus, London, United Kingdom, Division of Biostatistics, University of Minnesota, Minneapolis, Minnesota, United States of America

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• Mattia C. F. Prosperi,

  Affiliation Department of Pathology, Immunology and Laboratory Medicine, Emerging Pathogens Institute, College of Medicine, University of Florida, Gainesville, Florida, United States of America

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• Jesper Kjær,

  Affiliation Copenhagen HIV Programme, University of Copenhagen, Panum Institute, Copenhagen, Denmark

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• David Dunn,

  Affiliation Medical Research Council Clinical Trials Unit, London, United Kingdom

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• Roger Paredes,

  Affiliation HIV Unit and irsiCaixa Retrovirology Lab, Hospital Universitari Germans Trias i Pujol, Barcelona, Spain

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• Caroline A. Sabin,

  Affiliation Department of Infection and Population Health, Division of Population Health, UCL Medical School, Royal Free Campus, London, United Kingdom

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• Jens D. Lundgren,

  Affiliations Copenhagen HIV Programme, University of Copenhagen, Panum Institute, Copenhagen, Denmark, Centre for Viral Disease, Department of Infectious Diseases, Copenhagen University Hospital, Copenhagen, Denmark

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• Andrew N. Phillips,

  Affiliation Department of Infection and Population Health, Division of Population Health, UCL Medical School, Royal Free Campus, London, United Kingdom

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• Deenan Pillay,

  Affiliation Department of Virology, University College London, London, United Kingdom

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• for the EuroSIDA and the United Kingdom CHIC/United Kingdom HDRD Studies