A Systems Genetics Approach Provides a Bridge from Discovered Genetic Variants to Biological Pathways in Rheumatoid Arthritis

• Hirofumi Nakaoka,

  Affiliation Division of Human Genetics, Department of Integrated Genetics, National Institute of Genetics, Mishima, Shizuoka, Japan

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• Tailin Cui,

  Affiliation Division of Molecular Life Science, School of Medicine, Tokai University, Isehara, Kanagawa, Japan

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• Atsushi Tajima,

  Affiliations Division of Molecular Life Science, School of Medicine, Tokai University, Isehara, Kanagawa, Japan, Department of Human Genetics and Public Health, Institute of Health Biosciences, The University of Tokusima Graduate School, Tokushima, Tokushima, Japan

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• Akira Oka,

  Affiliation Division of Molecular Life Science, School of Medicine, Tokai University, Isehara, Kanagawa, Japan

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• Shigeki Mitsunaga,

  Affiliation Division of Molecular Life Science, School of Medicine, Tokai University, Isehara, Kanagawa, Japan

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• Koichi Kashiwase,

  Affiliation Department of Laboratory, Japanese Red Cross Tokyo Blood Center, Koto-ku, Tokyo, Japan

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• Yasuhiko Homma,

  Affiliation Department of Clinical Health Science, Tokai University School of Medicine, Isehara, Kanagawa, Japan

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• Shinji Sato,

  Affiliation Department of Internal Medicine, Division of Rheumatology, Tokai University School of Medicine, Isehara, Kanagawa, Japan

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• Yasuo Suzuki,

  Affiliation Department of Internal Medicine, Division of Rheumatology, Tokai University School of Medicine, Isehara, Kanagawa, Japan

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• Hidetoshi Inoko,

  Affiliation Division of Molecular Life Science, School of Medicine, Tokai University, Isehara, Kanagawa, Japan

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• Ituro Inoue

  * E-mail: itinoue@lab.nig.ac.jp

  Affiliations Division of Human Genetics, Department of Integrated Genetics, National Institute of Genetics, Mishima, Shizuoka, Japan, Division of Molecular Life Science, School of Medicine, Tokai University, Isehara, Kanagawa, Japan

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