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Research Article

A Selectable and Excisable Marker System for the Rapid Creation of Recombinant Poxviruses

  • Julia L. Rintoul equal contributor,

    equal contributor Contributed equally to this work with: Julia L. Rintoul, Jiahu Wang

    Affiliations: Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Canada, Centre for Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Canada

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  • Jiahu Wang equal contributor,

    equal contributor Contributed equally to this work with: Julia L. Rintoul, Jiahu Wang

    Affiliation: Centre for Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Canada

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  • Don B. Gammon,

    Affiliation: Department of Medical Microbiology and Immunology, Faculty of Medicine and Dentistry, Li Ka Shing Institute of Virology, University of Alberta, Edmonton, Canada

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  • Nicholas J. van Buuren,

    Affiliation: Department of Medical Microbiology and Immunology, Faculty of Medicine and Dentistry, Li Ka Shing Institute of Virology, University of Alberta, Edmonton, Canada

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  • Kenneth Garson,

    Affiliation: Centre for Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Canada

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  • Karen Jardine,

    Affiliation: Centre for Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Canada

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  • Michele Barry,

    Affiliation: Department of Medical Microbiology and Immunology, Faculty of Medicine and Dentistry, Li Ka Shing Institute of Virology, University of Alberta, Edmonton, Canada

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  • David H. Evans,

    Affiliation: Department of Medical Microbiology and Immunology, Faculty of Medicine and Dentistry, Li Ka Shing Institute of Virology, University of Alberta, Edmonton, Canada

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  • John C. Bell mail

    jbell@ohri.ca

    Affiliations: Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Canada, Centre for Cancer Therapeutics, Ottawa Hospital Research Institute, Ottawa, Canada

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  • Published: September 08, 2011
  • DOI: 10.1371/journal.pone.0024643

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