A Candidate HIV/AIDS Vaccine (MVA-B) Lacking Vaccinia Virus Gene C6L Enhances Memory HIV-1-Specific T-Cell Responses

Juan García-Arriaza; José Luis Nájera; Carmen E. Gómez; Nolawit Tewabe; Carlos Oscar S. Sorzano; Thierry Calandra; Thierry Roger; Mariano Esteban

doi:10.1371/journal.pone.0024244

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Peer-reviewed

Research Article

A Candidate HIV/AIDS Vaccine (MVA-B) Lacking Vaccinia Virus Gene C6L Enhances Memory HIV-1-Specific T-Cell Responses

Juan García-Arriaza,

Affiliation Department of Molecular and Cellular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain
⨯
José Luis Nájera,

Affiliation Department of Molecular and Cellular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain
⨯
Carmen E. Gómez,

Affiliation Department of Molecular and Cellular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain
⨯
Nolawit Tewabe,

Current address: Takeda Pharmaceutical Company, London, United Kingdom

Affiliation Department of Molecular and Cellular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain
⨯
Carlos Oscar S. Sorzano,

Affiliation Biocomputing Unit, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain
⨯
Thierry Calandra,

Affiliation Infectious Diseases Service, Department of Medicine, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland
⨯
Thierry Roger,

Affiliation Infectious Diseases Service, Department of Medicine, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland
⨯
Mariano Esteban

* E-mail: mesteban@cnb.csic.es

Affiliation Department of Molecular and Cellular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CSIC), Madrid, Spain
⨯

A Candidate HIV/AIDS Vaccine (MVA-B) Lacking Vaccinia Virus Gene C6L Enhances Memory HIV-1-Specific T-Cell Responses

Juan García-Arriaza,
José Luis Nájera,
Carmen E. Gómez,
Nolawit Tewabe,
Carlos Oscar S. Sorzano,
Thierry Calandra,
Thierry Roger,
Mariano Esteban

x

Published: August 31, 2011
https://doi.org/10.1371/journal.pone.0024244

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T cells
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HIV-1
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Immune response
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Cytotoxic T cells
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Enzyme-linked immunoassays
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HIV vaccines
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