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Open Access

Peer-reviewed

Research Article

Predictive Power Estimation Algorithm (PPEA) - A New Algorithm to Reduce Overfitting for Genomic Biomarker Discovery

  • Jiangang Liu,

    Affiliations Translational Science, Lilly Research Laboratories, a Division of Eli Lilly & Co., Indianapolis, Indiana, United States of America, School of Informatics, Indiana University-Purdue University Indianapolis, Indianapolis, Indiana, United States of America, Center for Computational Biology and Bioinformatics, School of Medicine, Indiana University, Indianapolis, Indiana, United States of America

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  • Robert A. Jolly,

    Affiliation Toxicology, Lilly Research Laboratories, a Division of Eli Lilly & Co., Indianapolis, Indiana, United States of America

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  • Aaron T. Smith,

    Affiliation Toxicology, Lilly Research Laboratories, a Division of Eli Lilly & Co., Indianapolis, Indiana, United States of America

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  • George H. Searfoss,

    Affiliation Toxicology, Lilly Research Laboratories, a Division of Eli Lilly & Co., Indianapolis, Indiana, United States of America

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  • Keith M. Goldstein,

    Affiliation Toxicology, Lilly Research Laboratories, a Division of Eli Lilly & Co., Indianapolis, Indiana, United States of America

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  • Vladimir N. Uversky,

    Affiliations Center for Computational Biology and Bioinformatics, School of Medicine, Indiana University, Indianapolis, Indiana, United States of America, Department of Molecular Medicine, University of South Florida, Tampa, Florida, United States of America, Institute for Biological Instrumentation, Russian Academy of Sciences, Pushchino, Moscow Region, Russia

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  • Keith Dunker,

    Affiliations School of Informatics, Indiana University-Purdue University Indianapolis, Indianapolis, Indiana, United States of America, Center for Computational Biology and Bioinformatics, School of Medicine, Indiana University, Indianapolis, Indiana, United States of America

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  • Shuyu Li,

    Affiliation Translational Science, Lilly Research Laboratories, a Division of Eli Lilly & Co., Indianapolis, Indiana, United States of America

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  • Craig E. Thomas ,

    weita@lilly.com (TW); cthomas@lilly.com (CET)

    Affiliation Toxicology, Lilly Research Laboratories, a Division of Eli Lilly & Co., Indianapolis, Indiana, United States of America

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  • Tao Wei

    weita@lilly.com (TW); cthomas@lilly.com (CET)

    Affiliation Translational Science, Lilly Research Laboratories, a Division of Eli Lilly & Co., Indianapolis, Indiana, United States of America

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