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Research Article

A Stratified Transcriptomics Analysis of Polygenic Fat and Lean Mouse Adipose Tissues Identifies Novel Candidate Obesity Genes

  • Nicholas M. Morton mail,

    nik.morton@ed.ac.uk

    Affiliation: Molecular Metabolism Group, BHF/University Centre for Cardiovascular Science, University of Edinburgh, Queen's Medical Research Institute, Edinburgh, United Kingdom

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  • Yvonne B. Nelson,

    Affiliation: Molecular Metabolism Group, BHF/University Centre for Cardiovascular Science, University of Edinburgh, Queen's Medical Research Institute, Edinburgh, United Kingdom

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  • Zoi Michailidou,

    Affiliation: Tissue Remodelling and Regeneration Group, Centre for Inflammation Research, Queen's Medical Research Institute, Edinburgh, United Kingdom

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  • Emma M. Di Rollo,

    Affiliation: Molecular Metabolism Group, BHF/University Centre for Cardiovascular Science, University of Edinburgh, Queen's Medical Research Institute, Edinburgh, United Kingdom

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  • Lynne Ramage,

    Affiliation: Molecular Metabolism Group, BHF/University Centre for Cardiovascular Science, University of Edinburgh, Queen's Medical Research Institute, Edinburgh, United Kingdom

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  • Patrick W. F. Hadoke,

    Affiliation: Endocrinology Unit, BHF/University Centre for Cardiovascular Science, University of Edinburgh, Queen's Medical Research Institute, Edinburgh, United Kingdom

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  • Jonathan R. Seckl,

    Affiliation: Endocrinology Unit, BHF/University Centre for Cardiovascular Science, University of Edinburgh, Queen's Medical Research Institute, Edinburgh, United Kingdom

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  • Lutz Bunger,

    Affiliation: Animal Breeding and Development Team, Sustainable Livestock Systems, SAC, Bush Estate, Penicuik, United Kingdom

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  • Simon Horvat,

    Affiliation: Animal Science Department, Biotechnical Faculty, University of Ljubljana, and National Institute of Chemistry, Hajdrihova, Ljubljana, Slovenia

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  • Christopher J. Kenyon,

    Affiliation: Endocrinology Unit, BHF/University Centre for Cardiovascular Science, University of Edinburgh, Queen's Medical Research Institute, Edinburgh, United Kingdom

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  • Donald R. Dunbar

    Affiliation: Bioinformatics Core, BHF/University Centre for Cardiovascular Science, University of Edinburgh, Queen's Medical Research Institute, Edinburgh, United Kingdom

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  • Published: September 07, 2011
  • DOI: 10.1371/journal.pone.0023944

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