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Systematic Spatial Bias in DNA Microarray Hybridization Is Caused by Probe Spot Position-Dependent Variability in Lateral Diffusion

  • Doris Steger ,

    Contributed equally to this work with: Doris Steger, David Berry

    Affiliation Department of Microbial Ecology, Vienna Ecology Center, Faculty of Life Sciences, University of Vienna, Wien, Austria

  • David Berry ,

    Contributed equally to this work with: Doris Steger, David Berry

    Affiliation Department of Microbial Ecology, Vienna Ecology Center, Faculty of Life Sciences, University of Vienna, Wien, Austria

  • Susanne Haider,

    Affiliation Department of Microbial Ecology, Vienna Ecology Center, Faculty of Life Sciences, University of Vienna, Wien, Austria

  • Matthias Horn,

    Affiliation Department of Microbial Ecology, Vienna Ecology Center, Faculty of Life Sciences, University of Vienna, Wien, Austria

  • Michael Wagner,

    Affiliation Department of Microbial Ecology, Vienna Ecology Center, Faculty of Life Sciences, University of Vienna, Wien, Austria

  • Roman Stocker,

    Affiliation Ralph M. Parsons Laboratory, Department of Civil and Environmental Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

  • Alexander Loy

    loy@microbial-ecology.net

    Affiliation Department of Microbial Ecology, Vienna Ecology Center, Faculty of Life Sciences, University of Vienna, Wien, Austria

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