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ATR-p53 Restricts Homologous Recombination in Response to Replicative Stress but Does Not Limit DNA Interstrand Crosslink Repair in Lung Cancer Cells

  • Bianca M. Sirbu,

    Affiliation Laboratory of Cellular and Molecular Radiation Oncology, Massachusetts General Hospital Cancer Center, Charlestown, Massachusetts, United States of America

  • Sarah J. Lachmayer ,

    Contributed equally to this work with: Sarah J. Lachmayer, Verena Wülfing, Lara M. Marten

    Affiliations Laboratory of Cellular and Molecular Radiation Oncology, Massachusetts General Hospital Cancer Center, Charlestown, Massachusetts, United States of America, Department of Radiation Oncology, University of Hamburg, Hamburg, Germany

  • Verena Wülfing ,

    Contributed equally to this work with: Sarah J. Lachmayer, Verena Wülfing, Lara M. Marten

    Affiliations Laboratory of Cellular and Molecular Radiation Oncology, Massachusetts General Hospital Cancer Center, Charlestown, Massachusetts, United States of America, Department of Radiation Oncology, University of Hamburg, Hamburg, Germany

  • Lara M. Marten ,

    Contributed equally to this work with: Sarah J. Lachmayer, Verena Wülfing, Lara M. Marten

    Affiliations Laboratory of Cellular and Molecular Radiation Oncology, Massachusetts General Hospital Cancer Center, Charlestown, Massachusetts, United States of America, Department of Radiation Oncology, University of Hamburg, Hamburg, Germany

  • Katie E. Clarkson,

    Affiliation Laboratory of Cellular and Molecular Radiation Oncology, Massachusetts General Hospital Cancer Center, Charlestown, Massachusetts, United States of America

  • Linda W. Lee,

    Affiliation Laboratory of Cellular and Molecular Radiation Oncology, Massachusetts General Hospital Cancer Center, Charlestown, Massachusetts, United States of America

  • Liliana Gheorghiu,

    Affiliation Laboratory of Cellular and Molecular Radiation Oncology, Massachusetts General Hospital Cancer Center, Charlestown, Massachusetts, United States of America

  • Lee Zou,

    Affiliations Center for Cancer Research, Massachusetts General Hospital Cancer Center, Charlestown, Massachusetts, United States of America, Institute of Radiobiology and Molecular Radiation Oncology, University of Marburg, Marburg, Germany

  • Simon N. Powell,

    Affiliation Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America

  • Jochen Dahm-Daphi,

    Affiliations Department of Radiation Oncology, University of Hamburg, Hamburg, Germany, Institute of Radiobiology and Molecular Radiation Oncology, University of Marburg, Marburg, Germany

  • Henning Willers

    hwillers@partners.org

    Affiliations Laboratory of Cellular and Molecular Radiation Oncology, Massachusetts General Hospital Cancer Center, Charlestown, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

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