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MicroRNA 144 Impairs Insulin Signaling by Inhibiting the Expression of Insulin Receptor Substrate 1 in Type 2 Diabetes Mellitus

  • Dwi Setyowati Karolina,

    Affiliation Department of Biochemistry, Yong Loo Lin School of Medicine, National University Health System, National University of Singapore, Singapore, Singapore

  • Arunmozhiarasi Armugam,

    Affiliation Department of Biochemistry, Yong Loo Lin School of Medicine, National University Health System, National University of Singapore, Singapore, Singapore

  • Subramaniam Tavintharan,

    Affiliation Department of Medicine, Khoo Teck Puat Hospital, Singapore, Singapore

  • Michael T. K. Wong,

    Affiliation Department of Medicine, Khoo Teck Puat Hospital, Singapore, Singapore

  • Su Chi Lim,

    Affiliation Department of Medicine, Khoo Teck Puat Hospital, Singapore, Singapore

  • Chee Fang Sum,

    Affiliation Department of Medicine, Khoo Teck Puat Hospital, Singapore, Singapore

  • Kandiah Jeyaseelan

    bchjeya@nus.edu.sg

    Affiliations Department of Biochemistry, Yong Loo Lin School of Medicine, National University Health System, National University of Singapore, Singapore, Singapore, Department of Anatomy and Developmental Biology, School of Biomedical Sciences, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Victoria, Australia

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