Comparative Expression Profile of miRNA and mRNA in Primary Peripheral Blood Mononuclear Cells Infected with Human Immunodeficiency Virus (HIV-1)

Ankit Gupta; Pruthvi Nagilla; Hai-Son Le; Coulton Bunney; Courtney Zych; Anbupalam Thalamuthu; Ziv Bar-Joseph; Sinnakaruppan Mathavan; Velpandi Ayyavoo

doi:10.1371/journal.pone.0022730

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Open Access

Peer-reviewed

Research Article

Comparative Expression Profile of miRNA and mRNA in Primary Peripheral Blood Mononuclear Cells Infected with Human Immunodeficiency Virus (HIV-1)

Ankit Gupta ,

Contributed equally to this work with: Ankit Gupta, Pruthvi Nagilla

Affiliation Department of Infectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Pruthvi Nagilla ,

Contributed equally to this work with: Ankit Gupta, Pruthvi Nagilla

Affiliation Department of Infectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Hai-Son Le,

Affiliation Department of Machine Learning, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America
⨯
Coulton Bunney,

Affiliation Department of Infectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Courtney Zych,

Affiliation Department of Infectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯
Anbupalam Thalamuthu,

Affiliation Human Genetics, Genome Institute of Singapore, Singapore
⨯
Ziv Bar-Joseph,

Affiliation Department of Machine Learning, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America
⨯
Sinnakaruppan Mathavan,

Affiliation Human Genetics, Genome Institute of Singapore, Singapore
⨯
Velpandi Ayyavoo

* E-mail: velpandi@pitt.edu

Affiliation Department of Infectious Diseases and Microbiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
⨯

Comparative Expression Profile of miRNA and mRNA in Primary Peripheral Blood Mononuclear Cells Infected with Human Immunodeficiency Virus (HIV-1)

Ankit Gupta,
Pruthvi Nagilla,
Hai-Son Le,
Coulton Bunney,
Courtney Zych,
Anbupalam Thalamuthu,
Ziv Bar-Joseph,
Sinnakaruppan Mathavan,
Velpandi Ayyavoo

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Published: July 28, 2011
https://doi.org/10.1371/journal.pone.0022730

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MicroRNAs
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HIV-1
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Host cells
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Virus effects on host gene expression
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Messenger RNA
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Post-transcriptional gene regulation
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MAPK signaling cascades
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Microarrays
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