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Why CCR2 and CCR5 Blockade Failed and Why CCR1 Blockade Might Still Be Effective in the Treatment of Rheumatoid Arthritis

  • Maria C. Lebre ,

    Contributed equally to this work with: Maria C. Lebre, Clarissa E. Vergunst

    c.lebre@amc.uva.nl

    Affiliation Division of Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, The Netherlands

  • Clarissa E. Vergunst ,

    Contributed equally to this work with: Maria C. Lebre, Clarissa E. Vergunst

    Affiliation Division of Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, The Netherlands

  • Ivy Y. K. Choi,

    Affiliation Division of Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, The Netherlands

  • Saïda Aarrass,

    Affiliation Division of Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, The Netherlands

  • Ana S. F. Oliveira,

    Affiliation Division of Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, The Netherlands

  • Tim Wyant,

    Affiliation Millennium Pharmaceuticals, Cambridge, Massachusetts, United States of America

  • Richard Horuk,

    Affiliation Department of Pharmacology, University of California Davis, Davis, California, United States of America

  • Kris A. Reedquist,

    Affiliation Division of Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, The Netherlands

  • Paul P. Tak

    Affiliation Division of Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, The Netherlands

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