Discovery of Molecular Mechanisms of Traditional Chinese Medicinal Formula Si-Wu-Tang Using Gene Expression Microarray and Connectivity Map

• Zhining Wen,

  Affiliations National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, Arkansas, United States of America, College of Chemistry, Sichuan University, Chengdu, Sichuan, China

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• Zhijun Wang,

  Affiliation Department of Pharmaceutical Sciences and Center for Advancement of Drug Research and Evaluation, College of Pharmacy, Western University of Health Sciences, Pomona, California, United States of America

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• Steven Wang,

  Affiliation Department of Pharmaceutical Sciences and Center for Advancement of Drug Research and Evaluation, College of Pharmacy, Western University of Health Sciences, Pomona, California, United States of America

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• Ranadheer Ravula,

  Affiliation Department of Pharmaceutical Sciences and Center for Advancement of Drug Research and Evaluation, College of Pharmacy, Western University of Health Sciences, Pomona, California, United States of America

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• Lun Yang,

  Affiliations National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, Arkansas, United States of America, Department of Clinical Pharmacy and Center for Pharmacogenomics, School of Pharmacy, Fudan University, Shanghai, China

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• Jun Xu,

  Affiliation Clinical Transcriptional Genomics Core, Medical Genetics Institute, Cedars-Sinai Medical Center, David Geffen School of Medicine at UCLA, Los Angeles, California, United States of America

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• Charles Wang,

  Affiliation Functional Genomics Core, Beckman Research Institute, City of Hope Comprehensive Cancer Center, Duarte, California, United States of America

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• Zhong Zuo,

  Affiliation School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China

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• Moses S. S. Chow,

  Affiliation Department of Pharmaceutical Sciences and Center for Advancement of Drug Research and Evaluation, College of Pharmacy, Western University of Health Sciences, Pomona, California, United States of America

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• Leming Shi ,

  * E-mail: leming.shi@gmail.com (LS); yhuang@westernu.edu (YH)

  Affiliations National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, Arkansas, United States of America, Department of Clinical Pharmacy and Center for Pharmacogenomics, School of Pharmacy, Fudan University, Shanghai, China

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• Ying Huang

  * E-mail: leming.shi@gmail.com (LS); yhuang@westernu.edu (YH)

  Affiliation Department of Pharmaceutical Sciences and Center for Advancement of Drug Research and Evaluation, College of Pharmacy, Western University of Health Sciences, Pomona, California, United States of America

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