Nerve Agent Hydrolysis Activity Designed into a Human Drug Metabolism Enzyme

• Andrew C. Hemmert,

  Affiliation Department of Biochemistry/Biophysics and Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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• Tamara C. Otto,

  Affiliation United States Army Medical Research Institute for Chemical Defense, Aberdeen Proving Ground, Maryland, United States of America

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• Roberto A. Chica,

  Current address: Department of Chemistry, University of Ottawa, Ottawa, Canada

  Affiliation Department of Biology and Chemistry, California Institute of Technology, Pasadena, California, United States of America

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• Monika Wierdl,

  Affiliation Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America

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• Jonathan S. Edwards,

  Affiliation Department of Biochemistry/Biophysics and Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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• Steven L. Lewis,

  Affiliation Department of Biochemistry/Biophysics and Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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• Carol C. Edwards,

  Affiliation Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America

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• Lyudmila Tsurkan,

  Affiliation Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America

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• C. Linn Cadieux,

  Affiliation United States Army Medical Research Institute for Chemical Defense, Aberdeen Proving Ground, Maryland, United States of America

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• Shane A. Kasten,

  Affiliation United States Army Medical Research Institute for Chemical Defense, Aberdeen Proving Ground, Maryland, United States of America

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• John R. Cashman,

  Affiliation Human BioMolecular Research Institute, San Diego, California, United States of America

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• Stephen L. Mayo,

  Affiliation Department of Biology and Chemistry, California Institute of Technology, Pasadena, California, United States of America

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• Philip M. Potter,

  Affiliation Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America

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• Douglas M. Cerasoli,

  Affiliation United States Army Medical Research Institute for Chemical Defense, Aberdeen Proving Ground, Maryland, United States of America

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• Matthew R. Redinbo

  * E-mail: redinbo@unc.edu

  Affiliation Department of Biochemistry/Biophysics and Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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