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Novel Sulfated Polysaccharides Disrupt Cathelicidins, Inhibit RAGE and Reduce Cutaneous Inflammation in a Mouse Model of Rosacea

  • Jianxing Zhang,

    Affiliations Center for Therapeutic Biomaterials, University of Utah, Salt Lake City, Utah, United States of America, Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah, United States of America

  • Xiaoyu Xu,

    Affiliations Center for Therapeutic Biomaterials, University of Utah, Salt Lake City, Utah, United States of America, Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah, United States of America

  • Narayanam V. Rao,

    Affiliation Department of Internal Medicine, University of Utah, Salt Lake City, Utah, United States of America

  • Brian Argyle,

    Affiliation Center for Therapeutic Biomaterials, University of Utah, Salt Lake City, Utah, United States of America

  • Lindsi McCoard,

    Affiliation Center for Therapeutic Biomaterials, University of Utah, Salt Lake City, Utah, United States of America

  • William J. Rusho,

    Affiliation Department of Pharmaceutics and Pharmaceutical Chemistry, University of Utah, Salt Lake City, Utah, United States of America

  • Thomas P. Kennedy ,

    tkennedy@mail.mcg.edu

    Affiliation Department of Internal Medicine, University of Utah, Salt Lake City, Utah, United States of America

  • Glenn D. Prestwich,

    Affiliations Center for Therapeutic Biomaterials, University of Utah, Salt Lake City, Utah, United States of America, Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah, United States of America

  • Gerald Krueger

    Affiliation Department of Dermatology, University of Utah, Salt Lake City, Utah, United States of America

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