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A Broadly Flavivirus Cross-Neutralizing Monoclonal Antibody that Recognizes a Novel Epitope within the Fusion Loop of E Protein

  • Yong-Qiang Deng ,

    Contributed equally to this work with: Yong-Qiang Deng, Jian-Xin Dai, Guang-Hui Ji

    Affiliation State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China

  • Jian-Xin Dai ,

    Contributed equally to this work with: Yong-Qiang Deng, Jian-Xin Dai, Guang-Hui Ji

    Affiliations International Joint Cancer Institute, Second Military Medical University, Shanghai, China, State Key Laboratory of Antibody Medicine and Targeted Therapy, Shanghai, China

  • Guang-Hui Ji ,

    Contributed equally to this work with: Yong-Qiang Deng, Jian-Xin Dai, Guang-Hui Ji

    Affiliation International Joint Cancer Institute, Second Military Medical University, Shanghai, China

  • Tao Jiang,

    Affiliation State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China

  • Hua-Jing Wang,

    Affiliations International Joint Cancer Institute, Second Military Medical University, Shanghai, China, State Key Laboratory of Antibody Medicine and Targeted Therapy, Shanghai, China

  • Hai-ou Yang,

    Affiliation State Key Laboratory of Antibody Medicine and Targeted Therapy, Shanghai, China

  • Weng-Long Tan,

    Affiliation State Key Laboratory of Antibody Medicine and Targeted Therapy, Shanghai, China

  • Ran Liu,

    Affiliation State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China

  • Man Yu,

    Affiliation State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China

  • Bao-Xue Ge,

    Affiliation Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences/Shanghai JiaoTong University School of Medicine, Shanghai, China

  • Qing-Yu Zhu,

    Affiliation State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China

  • E-De Qin,

    Affiliation State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China

  • Ya-Jun Guo ,

    yjguo@smmu.edu.cn (YJG); cfqin@hotmail.com (CFQ)

    Affiliations International Joint Cancer Institute, Second Military Medical University, Shanghai, China, State Key Laboratory of Antibody Medicine and Targeted Therapy, Shanghai, China

  • Cheng-Feng Qin

    yjguo@smmu.edu.cn (YJG); cfqin@hotmail.com (CFQ)

    Affiliation State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China

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