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Open Access

Peer-reviewed

Research Article

Effective Caspase Inhibition Blocks Neutrophil Apoptosis and Reveals Mcl-1 as Both a Regulator and a Target of Neutrophil Caspase Activation

  • David J. Wardle ,

    Contributed equally to this work with: David J. Wardle, Joseph Burgon

    Affiliation Medical Research Council Centre for Developmental and Biomedical Genetics, University of Sheffield, Sheffield, United Kingdom

    ⨯
  • Joseph Burgon ,

    Contributed equally to this work with: David J. Wardle, Joseph Burgon

    Affiliation Medical Research Council Centre for Developmental and Biomedical Genetics, University of Sheffield, Sheffield, United Kingdom

    ⨯
  • Ian Sabroe,

    Affiliation Department of Infection and Immunity, University of Sheffield, Sheffield, United Kingdom

    ⨯
  • Colin D. Bingle,

    Affiliation Department of Infection and Immunity, University of Sheffield, Sheffield, United Kingdom

    ⨯
  • Moira K. B. Whyte,

    Affiliations Medical Research Council Centre for Developmental and Biomedical Genetics, University of Sheffield, Sheffield, United Kingdom, Department of Infection and Immunity, University of Sheffield, Sheffield, United Kingdom

    ⨯
  • Stephen A. Renshaw

    s.a.renshaw@sheffield.ac.uk

    Affiliations Medical Research Council Centre for Developmental and Biomedical Genetics, University of Sheffield, Sheffield, United Kingdom, Department of Infection and Immunity, University of Sheffield, Sheffield, United Kingdom

    ⨯

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