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Open Access

Peer-reviewed

Research Article

Thermodynamic Additivity of Sequence Variations: An Algorithm for Creating High Affinity Peptides Without Large Libraries or Structural Information

  • Matthew P. Greving,

    Current address: The Scripps Research Institute, La Jolla, California, United States of America

    Affiliation Center for BioOptical Nanotechnology and Center for Innovations in Medicine, The Biodesign Institute, Arizona State University, Tempe, Arizona, United States of America

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  • Paul E. Belcher,

    Affiliation Center for BioOptical Nanotechnology and Center for Innovations in Medicine, The Biodesign Institute, Arizona State University, Tempe, Arizona, United States of America

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  • Chris W. Diehnelt,

    Affiliation Center for BioOptical Nanotechnology and Center for Innovations in Medicine, The Biodesign Institute, Arizona State University, Tempe, Arizona, United States of America

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  • Maria J. Gonzalez-Moa,

    Affiliation Center for BioOptical Nanotechnology and Center for Innovations in Medicine, The Biodesign Institute, Arizona State University, Tempe, Arizona, United States of America

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  • Jack Emery,

    Affiliation Center for BioOptical Nanotechnology and Center for Innovations in Medicine, The Biodesign Institute, Arizona State University, Tempe, Arizona, United States of America

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  • Jinglin Fu,

    Affiliation Center for BioOptical Nanotechnology and Center for Innovations in Medicine, The Biodesign Institute, Arizona State University, Tempe, Arizona, United States of America

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  • Stephen Albert Johnston,

    Affiliations Center for BioOptical Nanotechnology and Center for Innovations in Medicine, The Biodesign Institute, Arizona State University, Tempe, Arizona, United States of America, School of Life Sciences, Arizona State University, Tempe, Arizona, United States of America

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  • Neal W. Woodbury

    nwoodbury@asu.edu

    Affiliations Center for BioOptical Nanotechnology and Center for Innovations in Medicine, The Biodesign Institute, Arizona State University, Tempe, Arizona, United States of America, Department of Chemistry and Biochemistry, Arizona State University, Tempe, Arizona, United States of America

    ⨯

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