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Research Article

De Novo Designed Proteins from a Library of Artificial Sequences Function in Escherichia Coli and Enable Cell Growth

  • Michael A. Fisher,

    Affiliation: Departments of Chemistry and Molecular Biology, Princeton University, Princeton, New Jersey, United States of America

    Current address: Energy Biosciences Institute, University of California, Berkeley, California, United States of America

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  • Kara L. McKinley,

    Affiliation: Departments of Chemistry and Molecular Biology, Princeton University, Princeton, New Jersey, United States of America

    Current address: Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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  • Luke H. Bradley,

    Affiliation: Departments of Chemistry and Molecular Biology, Princeton University, Princeton, New Jersey, United States of America

    Current address: Departments of Anatomy and Neurobiology, Molecular and Cellular Biochemistry, University of Kentucky, Lexington, Kentucky, United States of America

    X
  • Sara R. Viola,

    Affiliation: Departments of Chemistry and Molecular Biology, Princeton University, Princeton, New Jersey, United States of America

    Current address: Columbia University Medical Center, New York, New York, United States of America

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  • Michael H. Hecht mail

    hecht@princeton.edu

    Affiliation: Departments of Chemistry and Molecular Biology, Princeton University, Princeton, New Jersey, United States of America

    X
  • Published: January 04, 2011
  • DOI: 10.1371/journal.pone.0015364

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