Influenza A Virus Hemagglutinin Antibody Escape Promotes Neuraminidase Antigenic Variation and Drug Resistance

Scott E. Hensley; Suman R. Das; James S. Gibbs; Adam L. Bailey; Loren M. Schmidt; Jack R. Bennink; Jonathan W. Yewdell

doi:10.1371/journal.pone.0015190

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Peer-reviewed

Research Article

Influenza A Virus Hemagglutinin Antibody Escape Promotes Neuraminidase Antigenic Variation and Drug Resistance

Scott E. Hensley,

Current address: The Wistar Institute, Philadelphia, Pennsylvania, United States of America

Affiliation Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America
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Suman R. Das,

Affiliation Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America
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James S. Gibbs,

Affiliation Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America
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Adam L. Bailey,

Affiliation Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America
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Loren M. Schmidt,

Affiliation Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America
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Jack R. Bennink,

Affiliation Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America
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Jonathan W. Yewdell

* E-mail: jyewdell@niaid.nih.gov

Affiliation Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, United States of America
⨯

Influenza A Virus Hemagglutinin Antibody Escape Promotes Neuraminidase Antigenic Variation and Drug Resistance

Scott E. Hensley,
Suman R. Das,
James S. Gibbs,
Adam L. Bailey,
Loren M. Schmidt,
Jack R. Bennink,
Jonathan W. Yewdell

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Published: February 22, 2011
https://doi.org/10.1371/journal.pone.0015190

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Influenza A virus
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Antigenic variation
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