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Research Article

Targeting Vascular NADPH Oxidase 1 Blocks Tumor Angiogenesis through a PPARα Mediated Mechanism

  • Sarah Garrido-Urbani,

    Affiliation: Department of Pathology and Immunology, Centre Médical Universitaire, University of Geneva, Geneva, Switzerland

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  • Stephane Jemelin,

    Affiliation: Department of Pathology and Immunology, Centre Médical Universitaire, University of Geneva, Geneva, Switzerland

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  • Christine Deffert,

    Affiliation: Department of Pathology and Immunology, Centre Médical Universitaire, University of Geneva, Geneva, Switzerland

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  • Stéphanie Carnesecchi,

    Affiliations: Department of Pathology and Immunology, Centre Médical Universitaire, University of Geneva, Geneva, Switzerland, Department of Pediatrics, Centre Médical Universitaire, University of Geneva, Geneva, Switzerland

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  • Olivier Basset,

    Affiliation: Department of Pathology and Immunology, Centre Médical Universitaire, University of Geneva, Geneva, Switzerland

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  • Cédric Szyndralewiez,

    Affiliation: GenKyoTex S.A., Geneva, Switzerland

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  • Freddy Heitz,

    Affiliation: GenKyoTex S.A., Geneva, Switzerland

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  • Patrick Page,

    Affiliation: GenKyoTex S.A., Geneva, Switzerland

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  • Xavier Montet,

    Affiliation: Department of Physiology and Metabolism, Centre Médical Universitaire, University of Geneva, Geneva, Switzerland

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  • Liliane Michalik,

    Affiliation: Center for Integrative Genomics, University of Lausanne, Lausanne, Switzerland

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  • Jack Arbiser,

    Affiliation: Department of Dermatology, Emory University School of Medicine, Atlanta, Georgia, United States of America

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  • Curzio Rüegg,

    Affiliation: Department of Medicine, Faculty of Science, University of Fribourg, Fribourg, Switzerland

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  • Karl Heinz Krause,

    Affiliation: Department of Pathology and Immunology, Centre Médical Universitaire, University of Geneva, Geneva, Switzerland

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  • Beat Imhof mail

    beat.imhof@unige.ch

    Affiliation: Department of Pathology and Immunology, Centre Médical Universitaire, University of Geneva, Geneva, Switzerland

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  • Published: February 07, 2011
  • DOI: 10.1371/journal.pone.0014665

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