Site-Specific Integration and Expression of an Anti-Malarial Gene in Transgenic Anopheles gambiae Significantly Reduces Plasmodium Infections

• Janet M. Meredith ,

  Contributed equally to this work with: Janet M. Meredith, Sanjay Basu

  Affiliation Centre for Applied Entomology and Parasitology, Keele University, Keele, United Kingdom

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• Sanjay Basu ,

  Contributed equally to this work with: Janet M. Meredith, Sanjay Basu

  Affiliations Centre for Applied Entomology and Parasitology, Keele University, Keele, United Kingdom, Department of Entomology, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States of America

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• Derric D. Nimmo,

  Affiliations Centre for Applied Entomology and Parasitology, Keele University, Keele, United Kingdom, Oxitec Ltd, Milton Park, Oxford, United Kingdom

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• Isabelle Larget-Thiery,

  Affiliation Institut Pasteur, Center for Production and Infection of Anopheles, Parasitology and Mycology Department, Paris, France

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• Emma L. Warr,

  Affiliation Centre for Applied Entomology and Parasitology, Keele University, Keele, United Kingdom

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• Ann Underhill,

  Affiliation Centre for Applied Entomology and Parasitology, Keele University, Keele, United Kingdom

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• Clare C. McArthur,

  Affiliation Centre for Applied Entomology and Parasitology, Keele University, Keele, United Kingdom

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• Victoria Carter,

  Affiliation Centre for Applied Entomology and Parasitology, Keele University, Keele, United Kingdom

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• Hilary Hurd,

  Affiliation Centre for Applied Entomology and Parasitology, Keele University, Keele, United Kingdom

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• Catherine Bourgouin,

  Affiliation Institut Pasteur, Center for Production and Infection of Anopheles, Parasitology and Mycology Department, Paris, France

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• Paul Eggleston

  * E-mail: p.eggleston@biol.keele.ac.uk.

  Affiliation Centre for Applied Entomology and Parasitology, Keele University, Keele, United Kingdom

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