Perifosine and CCI 779 Co-Operate to Induce Cell Death and Decrease Proliferation in PTEN-Intact and PTEN-Deficient PDGF-Driven Murine Glioblastoma

• Kenneth L. Pitter,

  Affiliations Department of Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America, Brain Tumor Center, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

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• Craig J. Galbán,

  Affiliation Departments of Radiology, The University of Michigan Medical School, Ann Arbor, Michigan, United States of America

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• Stefanie Galbán,

  Affiliation Radiation Oncology, The University of Michigan Medical School, Ann Arbor, Michigan, United States of America

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• Omid Saeed-Tehrani,

  Affiliation Departments of Radiology, The University of Michigan Medical School, Ann Arbor, Michigan, United States of America

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• Fei Li,

  Affiliation Departments of Radiology, The University of Michigan Medical School, Ann Arbor, Michigan, United States of America

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• Nikki Charles,

  Affiliations Department of Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America, Brain Tumor Center, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

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• Michelle S. Bradbury,

  Affiliation Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

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• Oren J. Becher,

  Affiliations Department of Pediatrics, Duke University Medical Center, Durham, North Carolina, United States of America, Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina, United States of America

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• Thomas L. Chenevert,

  Affiliation Departments of Radiology, The University of Michigan Medical School, Ann Arbor, Michigan, United States of America

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• Alnawaz Rehemtulla,

  Affiliation Radiation Oncology, The University of Michigan Medical School, Ann Arbor, Michigan, United States of America

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• Brian D. Ross ,

  * E-mail: hollande@mskcc.org (ECH); hambard@ccf.org (DH); bdross@umich.edu (BDR)

  Affiliation Departments of Radiology, The University of Michigan Medical School, Ann Arbor, Michigan, United States of America

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• Eric C. Holland ,

  * E-mail: hollande@mskcc.org (ECH); hambard@ccf.org (DH); bdross@umich.edu (BDR)

  Affiliations Department of Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America, Brain Tumor Center, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America, Departments of Neurosurgery, Neurology and Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

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• Dolores Hambardzumyan

  * E-mail: hollande@mskcc.org (ECH); hambard@ccf.org (DH); bdross@umich.edu (BDR)

  Affiliation Department of Stem Cell Biology and Regenerative Medicine in Lerner Research Institute at Cleveland Clinic, Cleveland, Ohio, United States of America

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