Generation of Human Antigen-Specific Monoclonal IgM Antibodies Using Vaccinated “Human Immune System” Mice

• Pablo D. Becker ,

  Contributed equally to this work with: Pablo D. Becker, Nicolas Legrand

  Affiliation Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research (HZI), Braunschweig, Germany

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• Nicolas Legrand ,

  Contributed equally to this work with: Pablo D. Becker, Nicolas Legrand

  Affiliation Department of Cell Biology and Histology, Academic Medical Center of the University of Amsterdam (AMC-UvA), Center for Immunology Amsterdam (CIA), Amsterdam, The Netherlands

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• Caroline M. M. van Geelen,

  Affiliation AIMM Therapeutics, Amsterdam, The Netherlands

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• Miriam Noerder,

  Affiliation Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research (HZI), Braunschweig, Germany

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• Nicholas D. Huntington,

  Affiliations Cytokines and Lymphoid Development Unit, Institut Pasteur, Paris, France, INSERM U668, Institut Pasteur, Paris, France

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• Annick Lim,

  Affiliation INSERM U668, Institut Pasteur, Paris, France

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• Etsuko Yasuda,

  Current address: Department of Medicine, University of Vermont, Burlington, Vermont, United States of America

  Affiliation AIMM Therapeutics, Amsterdam, The Netherlands

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• Sean A. Diehl,

  Current address: Department of Medicine, University of Vermont, Burlington, Vermont, United States of America

  Affiliation Department of Cell Biology and Histology, Academic Medical Center of the University of Amsterdam (AMC-UvA), Center for Immunology Amsterdam (CIA), Amsterdam, The Netherlands

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• Ferenc A. Scheeren,

  Current address: Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Palo Alto, California, United States of America

  Affiliation Department of Cell Biology and Histology, Academic Medical Center of the University of Amsterdam (AMC-UvA), Center for Immunology Amsterdam (CIA), Amsterdam, The Netherlands

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• Michael Ott,

  Affiliation Clinic for Gastroenterology, Hepatology, and Endocrinology, Hannover Medical School, Twincore Centre of Experimental and Clinical Infection Research, Hannover, Germany

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• Kees Weijer,

  Affiliation Department of Cell Biology and Histology, Academic Medical Center of the University of Amsterdam (AMC-UvA), Center for Immunology Amsterdam (CIA), Amsterdam, The Netherlands

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• Heiner Wedemeyer,

  Affiliation Clinic for Gastroenterology, Hepatology, and Endocrinology, Hannover Medical School, Twincore Centre of Experimental and Clinical Infection Research, Hannover, Germany

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• James P. Di Santo,

  Affiliations Cytokines and Lymphoid Development Unit, Institut Pasteur, Paris, France, INSERM U668, Institut Pasteur, Paris, France

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• Tim Beaumont,

  Affiliation AIMM Therapeutics, Amsterdam, The Netherlands

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• Carlos A. Guzman,

  Affiliation Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research (HZI), Braunschweig, Germany

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•  [ ... ],
• Hergen Spits

  * E-mail: Hergen.Spits@amc.uva.nl

  Affiliations Department of Cell Biology and Histology, Academic Medical Center of the University of Amsterdam (AMC-UvA), Center for Immunology Amsterdam (CIA), Amsterdam, The Netherlands, AIMM Therapeutics, Amsterdam, The Netherlands

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