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Open Access

Peer-reviewed

Research Article

Rad21-Cohesin Haploinsufficiency Impedes DNA Repair and Enhances Gastrointestinal Radiosensitivity in Mice

  • Huiling Xu,

    Affiliations Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia, Department of Pathology, Faculty of Medicine and Dental Sciences, The University of Melbourne, Parkville, Victoria, Australia

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  • Kuhendra Balakrishnan,

    Affiliation Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia

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  • Jordane Malaterre,

    Affiliation Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia

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  • Matthew Beasley,

    Affiliation Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia

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  • Yuqian Yan,

    Affiliation Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia

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  • Jeroen Essers,

    Affiliation Department of Cell Biology and Genetics, Erasmus Medical Centre, Rotterdam, The Netherlands

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  • Esther Appeldoorn,

    Affiliation Department of Cell Biology and Genetics, Department of Radiobiology, Department of Vascular Surgery, Erasmus Medical Centre, Rotterdam, The Netherlands

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  • Jonathan M. Thomaszewski,

    Affiliation Division of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia

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  • Melisa Vazquez,

    Affiliation Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia

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  • Sandra Verschoor,

    Affiliation Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia

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  • Martin F. Lavin,

    Affiliation Radiation Biology and Oncology, Queensland Institute of Medical Research, Queensland, Australia

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  • Ivan Bertonchello,

    Affiliation Department of Pharmacology, The University of Melbourne, Parkville, Victoria, Australia

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  • Robert G. Ramsay ,

    michael.mckay@act.gov.au (MJM); rob.ramsay@petermac.org (RGR)

    Affiliations Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia, Department of Pathology, Faculty of Medicine and Dental Sciences, The University of Melbourne, Parkville, Victoria, Australia

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  • Michael J. McKay

    michael.mckay@act.gov.au (MJM); rob.ramsay@petermac.org (RGR)

    Current address: Department of Radiation Oncology and Australian National University, Canberra Hospital, Garran, Australian Capital Territory, Australia

    Affiliations Research Division, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia, Division of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia

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