Prediction of Deleterious Non-Synonymous SNPs Based on Protein Interaction Network and Hybrid Properties

• Tao Huang ,

  Contributed equally to this work with: Tao Huang, Ping Wang, Zhi-Qiang Ye

  Affiliations Key Laboratory of Systems Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, People's Republic of China, Shanghai Center for Bioinformation Technology, Shanghai, People's Republic of China

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• Ping Wang ,

  Contributed equally to this work with: Tao Huang, Ping Wang, Zhi-Qiang Ye

  Affiliation Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences and Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China

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• Zhi-Qiang Ye ,

  Contributed equally to this work with: Tao Huang, Ping Wang, Zhi-Qiang Ye

  Affiliations Key Laboratory of Systems Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, People's Republic of China, Shanghai Center for Bioinformation Technology, Shanghai, People's Republic of China

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• Heng Xu,

  Affiliation Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences and Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China

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• Zhisong He,

  Affiliation CAS-MPG Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, People's Republic of China

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• Kai-Yan Feng,

  Affiliation Shanghai Center for Bioinformation Technology, Shanghai, People's Republic of China

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• LeLe Hu,

  Affiliation Institute of Systems Biology, Shanghai University, Shanghai, People's Republic of China

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• WeiRen Cui,

  Affiliation CAS-MPG Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, People's Republic of China

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• Kai Wang,

  Affiliation Institute of Systems Biology, Shanghai University, Shanghai, People's Republic of China

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• Xiao Dong,

  Affiliations Key Laboratory of Systems Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, People's Republic of China, Shanghai Center for Bioinformation Technology, Shanghai, People's Republic of China

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• Lu Xie,

  Affiliation Shanghai Center for Bioinformation Technology, Shanghai, People's Republic of China

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• Xiangyin Kong ,

  * E-mail: yxli@sibs.ac.cn (YL); cai_yud@yahoo.com.cn (YDC); xykong@sibs.ac.cn (XK)

  Affiliations Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences and Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China, State Key Laboratory of Medical Genomics, Ruijin Hospital, Shanghai Jiaotong University, Shanghai, People's Republic of China

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• Yu-Dong Cai ,

  * E-mail: yxli@sibs.ac.cn (YL); cai_yud@yahoo.com.cn (YDC); xykong@sibs.ac.cn (XK)

  Affiliations Institute of Systems Biology, Shanghai University, Shanghai, People's Republic of China, Centre for Computational Systems Biology, Fudan University, Shanghai, People's Republic of China

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• Yixue Li

  * E-mail: yxli@sibs.ac.cn (YL); cai_yud@yahoo.com.cn (YDC); xykong@sibs.ac.cn (XK)

  Affiliations Key Laboratory of Systems Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, People's Republic of China, Shanghai Center for Bioinformation Technology, Shanghai, People's Republic of China

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