NMR Structure of the Human Prion Protein with the Pathological Q212P Mutation Reveals Unique Structural Features

• Gregor Ilc ,

  Contributed equally to this work with: Gregor Ilc, Gabriele Giachin

  Affiliation Slovenian NMR Centre, National Institute of Chemistry, Ljubljana, Slovenia

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• Gabriele Giachin ,

  Contributed equally to this work with: Gregor Ilc, Gabriele Giachin

  Affiliation Laboratory of Prion Biology, Neurobiology Sector, Scuola Internazionale Superiore di Studi Avanzati (SISSA), Trieste, Italy

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• Mariusz Jaremko,

  Affiliation Laboratory of Biological NMR, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland

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• Łukasz Jaremko,

  Affiliations Laboratory of Biological NMR, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland, Faculty of Chemistry, Warsaw University, Warsaw, Poland

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• Federico Benetti,

  Affiliations Laboratory of Prion Biology, Neurobiology Sector, Scuola Internazionale Superiore di Studi Avanzati (SISSA), Trieste, Italy, SISSA Unit, Italian Institute of Technology, Trieste, Italy

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• Janez Plavec ,

  * E-mail: janez.plavec@ki.si (JP); legname@sissa.it (GL)

  Affiliations Slovenian NMR Centre, National Institute of Chemistry, Ljubljana, Slovenia, Faculty of Chemistry and Chemical Technology, University of Ljubljana, Ljubljana, Slovenia

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• Igor Zhukov,

  Affiliations Slovenian NMR Centre, National Institute of Chemistry, Ljubljana, Slovenia, Laboratory of Biological NMR, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland

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• Giuseppe Legname

  * E-mail: janez.plavec@ki.si (JP); legname@sissa.it (GL)

  Affiliations Laboratory of Prion Biology, Neurobiology Sector, Scuola Internazionale Superiore di Studi Avanzati (SISSA), Trieste, Italy, SISSA Unit, Italian Institute of Technology, Trieste, Italy, ELETTRA Laboratory, Sincrotrone Trieste S.C.p.A., Trieste, Italy

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