Splice-Site Mutations Cause Rrp6-Mediated Nuclear Retention of the Unspliced RNAs and Transcriptional Down-Regulation of the Splicing-Defective Genes

Open Access

Peer-reviewed

Research Article

Andrea B. Eberle,

Affiliation Department of Molecular Biology and Functional Genomics, Stockholm University, Stockholm, Sweden
⨯
Viktoria Hessle,

Affiliation Department of Molecular Biology and Functional Genomics, Stockholm University, Stockholm, Sweden
⨯
Roger Helbig,

Affiliation Department of Molecular Biology and Functional Genomics, Stockholm University, Stockholm, Sweden
⨯
Widad Dantoft,

Affiliation Department of Molecular Biology and Functional Genomics, Stockholm University, Stockholm, Sweden
⨯
Niclas Gimber,

Affiliation Department of Molecular Biology and Functional Genomics, Stockholm University, Stockholm, Sweden
⨯
Neus Visa

* E-mail: Neus.Visa@molbio.su.se

Affiliation Department of Molecular Biology and Functional Genomics, Stockholm University, Stockholm, Sweden
⨯

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Messenger RNA
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DNA transcription
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Introns
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Gene expression
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RNA interference
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Drosophila melanogaster
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Exosomes
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Mutation
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