Efficient Generation of Germ Line Transmitting Chimeras from C57BL/6N ES Cells by Aggregation with Outbred Host Embryos

• Marina Gertsenstein ,

  Contributed equally to this work with: Marina Gertsenstein, Lauryl M. J. Nutter

  Affiliations Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada, The Toronto Centre for Phenogenomics, Toronto, Ontario, Canada

  ⨯
• Lauryl M. J. Nutter ,

  Contributed equally to this work with: Marina Gertsenstein, Lauryl M. J. Nutter

  Affiliation The Hospital for Sick Children, Toronto, Ontario, Canada

  ⨯
• Tammy Reid,

  Affiliation Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada

  ⨯
• Monica Pereira,

  Affiliations Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada, The Toronto Centre for Phenogenomics, Toronto, Ontario, Canada

  ⨯
• William L. Stanford,

  Affiliation Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada

  ⨯
• Janet Rossant,

  Affiliations The Hospital for Sick Children, Toronto, Ontario, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada, Department of Obstetrics and Gynaecology, University of Toronto, Toronto, Ontario, Canada

  ⨯
• Andras Nagy

  * E-mail: nagy@mshri.on.ca

  Affiliations Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

  ⨯