Evaluation of Association of HNF1B Variants with Diverse Cancers: Collaborative Analysis of Data from 19 Genome-Wide Association Studies

• Katherine S. Elliott,

  Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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• Eleftheria Zeggini,

  Affiliations Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom, Applied Statistical Genetics, Wellcome Trust Sanger Institute, University of Cambridge, Cambridge, United Kingdom

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• Mark I. McCarthy,

  Affiliations Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom, Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, United Kingdom

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• Julius Gudmundsson,

  Affiliation deCODE Genetics, Reykjavik, Iceland

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• Patrick Sulem,

  Affiliation deCODE Genetics, Reykjavik, Iceland

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• Simon N. Stacey,

  Affiliation deCODE Genetics, Reykjavik, Iceland

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• Steinunn Thorlacius,

  Affiliation deCODE Genetics, Reykjavik, Iceland

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• Laufey Amundadottir,

  Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, United States of America

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• Henrik Grönberg,

  Affiliation Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden

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• Jianfeng Xu,

  Affiliations Center for Cancer Genomics, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States of America, Center for Human Genomics, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States of America

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• Valerie Gaborieau,

  Affiliation Genetic Epidemiology Group, International Agency for Research on Cancer (IARC), Lyon, France

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• Rosalind A. Eeles,

  Affiliation Oncogenetics Team, The Institute of Cancer Research, Sutton, United Kingdom

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• David E. Neal,

  Affiliation Department of Oncology, University of Cambridge, Cambridge, United Kingdom

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• Jenny L. Donovan,

  Affiliation Department of Social Medicine, University of Bristol, Bristol, United Kingdom

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• Freddie C. Hamdy,

  Affiliation Nuffield Department of Surgery, University of Oxford, Oxford, United Kingdom

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• Kenneth Muir,

  Affiliation Health Sciences Research Institute, University of Warwick, Coventry, United Kingdom

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• Shih-Jen Hwang,

  Affiliation Framingham Study, National Heart, Lung, and Blood Institute, Bethesda, Maryland, United States of America

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• Margaret R. Spitz,

  Affiliation Department of Epidemiology, M. D. Anderson Cancer Center, Houston, Texas, United States of America

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• Brent Zanke,

  Affiliations Ontario Institute for Cancer Research, MaRS Centre, Toronto, Ontario, Canada, Ottawa Health Research Institute, University of Ottawa, Ottawa, Ontario, Canada

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• Luis Carvajal-Carmona,

  Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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• Kevin M. Brown,

  Affiliation Integrated Cancer Genomics Division, The Translational Genomics Research Institute, Phoenix, Arizona, United States of America

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• Australian Melanoma Family Study Investigators ,

  ¶See acknowledgments for author list.

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• Nicholas K. Hayward,

  Affiliation Queensland Institute of Medical Research, Royal Brisbane Hospital, Brisbane, Queensland, Australia

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• Stuart Macgregor,

  Affiliation Queensland Institute of Medical Research, Royal Brisbane Hospital, Brisbane, Queensland, Australia

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• Ian P. M. Tomlinson,

  Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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• Mathieu Lemire,

  Affiliation Ontario Institute for Cancer Research, MaRS Centre, Toronto, Ontario, Canada

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• Christopher I. Amos,

  Affiliation Department of Epidemiology, M. D. Anderson Cancer Center, Houston, Texas, United States of America

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• Joanne M. Murabito,

  Affiliation Section of General Internal Medicine, Boston University School of Medicine, Boston, Massachusetts, United States of America

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• William B. Isaacs,

  Affiliation The Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America

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• Douglas F. Easton,

  Affiliation Cancer Research UK Genetic Epidemiology Unit, University of Cambridge, Cambridge, United Kingdom

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• Paul Brennan,

  Affiliation Genetic Epidemiology Group, International Agency for Research on Cancer (IARC), Lyon, France

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• The PanScan Consortium ,

  ¶See acknowledgments for author list.

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• Rosa B. Barkardottir,

  Affiliations Department of Pathology, Landspitali-University Hospital of Iceland, Reykjavik, Iceland, Faculty of Medicine, University of Iceland, Reykjavik, Iceland

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• Daniel F. Gudbjartsson,

  Affiliation deCODE Genetics, Reykjavik, Iceland

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• Thorunn Rafnar,

  Affiliation deCODE Genetics, Reykjavik, Iceland

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• David J. Hunter,

  Affiliation Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America

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• Stephen J. Chanock,

  Affiliation Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, United States of America

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• Kari Stefansson,

  Affiliation deCODE Genetics, Reykjavik, Iceland

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•  [ ... ],
• John P. A. Ioannidis

  * E-mail: jioannid@cc.uoi.gr

  Affiliations Department of Hygiene and Epidemiology, University of Ioannina School of Medicine and Biomedical Research Institute, Foundation for Research and Technology-Hellas, Ioannina, Greece, Center for Genetic Epidemiology and Modelling, Tufts University School of Medicine, Boston, Massachusetts, United States of America

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